
12460 S Us Highway 181
San Antonio, TX, 78223
Property Description
Located at 12460 S US Highway 181 in San Antonio, Texas, this versatile commercial property offers an excellent opportunity along one of the area's primary corridors connecting San Antonio to Floresville and the surrounding communities. 32+/- acre lot with convenient access to Loop 1604, the property benefits from strong visibility and easy accessibility in a rapidly growing area. The 1,895+/- square foot building features a functional layout that includes a full kitchen, two full bathrooms, and five additional rooms, making it well suited for a variety of office, medical, professional, or service-based uses.
With direct frontage on US Highway 181 and ample potential for owner-users or investors alike, this property offers flexibility in a highly accessible San Antonio location.
Property Details
- Property Type
- Single-Family Detached
- Style
- One Story
- Bedrooms
- 5
- Bathrooms
- 2.0
- Living Area
- 1,404 sqft
- Lot Size
- 0.32 acres
- Year Built
- 1979
- Price / Sq Ft
- $224/sqft
- County
- Bexar
- Subdivision
- EAST CENTRAL AREA
- School District
- East Central I.S.D
- Proposed Terms
- Conventional
- Status
- ACT
- Last Updated
- 07/28/2026
Location
12460 S Us Highway 181, San Antonio, TX, 78223
Explore the Area
Listed by Texas Landmen. Information deemed reliable but not guaranteed.




